the role of the histaminergic system on the inhibitory effect of ghrelin on feed intake in broiler chickens
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abstract
this study was conducted to investigate the possible involvement of the histaminergic system in themediation of ghrelin-induced feeding behavior in broiler chickens. in the trial 1, the effect ofintracerebroventricular (icv) injection of ghrelin on feed intake was examined in 3-h feed-deprived broilerchickens. in the trials 2 and 3, the chickens were received icv chlorpheniramine (an h1 receptor antagonist)and cimetidine (an h2 receptor antagonist) prior to ghrelin injection, respectively. cumulative feed intakewas measured at 3-h post injections. infusion of ghrelin (0.3, 0.6 and 1.2 nmol) decreased feed intake dosedependently (p
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Journal title:
iranian journal of veterinary researchPublisher: shiraz university
ISSN 1728-1997
volume 11
issue 1 2010
Keywords
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